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It is best known for encouraging sleep onset and controlling sleep-wake cycles

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Tesofensine works by inhibiting the reuptake of dopamine, norepinephrine, and serotonin, leading to appetite suppression and increased satiety

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Similarly, in lung cancer, tumor suppressor genes such as p16, RASSF1A, and KCNK3 undergo methylation-induced silencing, promoting tumor progression

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JAMA 327 , 885 (2022)

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